Hypertension’s link to dementia calls for stronger blood pressure control

How hypertension’s links to dementia make blood pressure control even more important

Links between dementia and hypertension are reasons to keep blood pressure under tighter control – sooner rather than later

The patient initially came to see Dr Mark Supiano in 2017 because her family was concerned about her short-term memory loss.

While taking her history and vital signs, Supiano, a geriatrician at the University of Utah, in the United States, saw that her blood pressure was 148/86: above normal despite her taking two medications intended to lower it. “Clearly that was too high,” he says.

Several factors could have contributed to the high reading, including the anti-inflammatory drug the 78-year-old woman took for arthritis pain, her high-sodium diet and lack of regular exercise. She also told Supiano that she typically drank a couple of glasses of wine each evening.

After Supiano discussed ways to reduce her risk, the woman and her husband joined a gym. She stopped taking the anti-inflammatory drug and cut back on salt and alcohol, bringing her systolic blood pressure readings into the 130-to-140 range – still

hypertensive, according to the guidelines issued by the American Heart Association (AHA) and the American College of Cardiology (ACC) later that year, but more acceptable.

Systolic pressure – the measurement of pressure when the heart beats and contracts – is the top number in the blood pressure ratio and the more clinically important number. The second number – diastolic – measures pressure between heartbeats.

By 2019, though, the patient had a diagnosis of mild cognitive impairment, and medical evidence was emerging about a connection between hypertension – high blood pressure – and dementia.

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